MLS Odds, Predictions, Picks for Week 25

Wednesday s MLS matches see LAFC listed as the biggest favorites at -175 odds over expansion side St. Louis City. San Jose and Seattle is seen as dead-even by oddsmakers with both teams priced at +162 in the MLS Week 25 odds and the draw being just +220.

Austin travels to Vancouver in one of the late games in great form. No team since June 21 has scored more goals (11) or recorded more points (10) than the Verde and Black. The Verde are big underdogs (+350) and the Over 2.5 is juiced to -188 in the MLS odds. Meanwhile, CF Montreal are big road underdogs at +350 as they have just one road win in 11 games and have only scored in three of those 11 road games.

Nashville has won 8/10 at home across all competitions and is undefeated in each of those past ten home games and wi…